Much of the manuscript material consists of Wolfe's research into Revolutionary and 19th century military medicine that was not included in his volume 3 of The medical department of the United States Army in the World War.

Letters while Jefferson Randolph Kean was Surgeon-General. Much of the correspondence relates to the bill to increase the efficiency of the Medical Dept. of the Army, forwarded by the War Dept. to Congress on Feb. 19, 1904. Correspondents extensive.